Acute on Chronic Liver Failure Due to Acute Hepatitis C

Acute-on-chronic liver failure develops in a setting of acute decompensation of chronic liver disease, associated with organ failure and high mortality rate. Many causes have been described as the “trigger event”. Viral hepatitis A, B and E is considered precipitating events and several studies have addressed this issue. Acute hepatitis C has been described as a cause of acute liver failure but no case of a worsening of a preexisting liver disease in this setting has been reported in the literature. We present the case of a 75-year old woman who suffered cirrhosis by non-alcoholic steatohepatitis and was infected with hepatitis virus C; who developed acute-on-chronic liver failure with a fatal evolution.